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Why We Used Nitrosigine In our FORMULER Pre-workout
- Eli Sommermeyer
- Nov 13, 2025
- 2 min read
Nitrosigine Overview
Nitrosigine is a patented complex of arginine and silicate that’s clinically proven to increase nitric oxide (NO) levels, which improves blood flow, muscle pumps, and focus during training. It’s designed to work faster and more efficiently than traditional nitric oxide ingredients like L-citrulline or L-arginine. The benifits of Nitrosigine are well documented. There are over 30 research studies available currently to back up Nitrosigine’s health claims.
Why we added Nitrosigine to the FORMULER
When we set out to create FORMULER, our goal wasn’t just to make another high-stim pre-workout. We wanted every ingredient to be there for a reason. That’s why we included Nitrosigine, one of the most effective nitric oxide boosters available today.
The FORMULER already contains 6 grams of L-Citrulline, a great dose for boosting nitric oxide. However, instead of raising that dose to 10 grams (which can sometimes cause stomach discomfort and diminishing returns), we decided to include 1.5 grams of Nitrosigine.
Here’s why:
A study from the University of Arkansas found that 1.5 grams of Nitrosigine could enhance blood flow and vasodilation to the same extent as 8 grams of Citrulline Malate. That means combining our 6g of Citrulline with 1.5g of Nitrosigine can deliver pump and performance effects similar to taking around 14 grams of L-Citrulline, without the bloat or fatigue that sometimes comes with high doses.
Unlike traditional nitric oxide ingredients that can take time to convert in the body, Nitrosigine works fast. Studies show it can start increasing blood flow and nitric oxide levels within 15 to 30 minutes of taking it.
The Benefits of Nitrosigine
Increased blood flow for better pumps and nutrient delivery*
Faster onset - works within 15–30 minutes*
Improved focus and cognitive performance*
Smoother digestion and cleaner energy compared to very high L-Citrulline doses*
The Bottom Line
We didn’t just want the FORMULER to look good on the label, we wanted it to perform. Nitrosigine gave us the edge we were looking for: a study-backed ingredient that enhances both pump and focus, making every scoop of FORMULER more effective.
6g Citrulline + 1.5g Nitrosigine = pump power equivalent to 14g Citrulline. That’s what smarter formulation looks like.
Read more about nitrosigine:
*These statements have not been evaluated by the Food and Drug Administration*